Michelle Witen obtained her DPhil from the University of Oxford, where she was also a Visiting Fellow in 2016, and holds an MA in Comparative Literature as well as a Scholars' Electives Honours BA in English and Comparative Literature from the University of Western Ontario. She has also worked at the University of Basel as an Oberassistentin.

Her monograph, James Joyce and Absolute Music (London: Blomsbury 2018) appeared in paperback in 2019, and examines Joyce's incorporation of musical structure across his opus. Other recent publications include a chapter on T. S. Eliot and music for the Edinburgh Companion to Eliot and the Arts (Edinburgh: EUP 2016)an article on Frankenstein  and hysteria (LA, Geneva: DoPe Press 2017), and a co-edited volume on Shakespeare and Space: Theatrical Explorations of the Spatial Paradigm (Houndmills: Palgrave 2016). She has also written articles on Joyce for Genetic Joyce Studies and Variations, and she has a forthcoming co-edited special issue of the James Joyce Quarterly on "Joyce and the Non-Human" and she is currently co-editing a volume on Modernism in Wonderland.

Her current research interests include 19th- and 20th-century British and Irish Literature, particularly within the contexts of music, interdisciplinarity, intermediality, and genetic criticism. Her second book focuses on 19th-century periodicals from 1850 onwards in the fiction of Thomas De Quincey, A. C. Doyle, Wilkie Collins, and Bram Stoker.